PSC2021 - Structural organic chemistry - 2018

Structural Organic Chemistry lays a foundation of knowledge about the structure and reactivity of the key functional groups found in pharmaceutical compounds. These general topics are relevant to drug design, the synthesis of bioactive molecules, drug-target interactions and drug formulation.

At the end of this unit students will develop:

1. A detailed knowledge of the structure of common functional groups contained in pharmaceuticals;
2. A detailed knowledge of the properties of functional groups, with a particular focus on steric, electronic and acid/base properties relevant to drug discovery and formulation;
3. An understanding of the reactivity of these functional groups;
4. An understanding of basic reaction mechanisms, kinetics and thermodynamics;
5. The practical ability to
   1. perform a basic chemical reaction
   2. purify the product(s)
   3. analyse and characterise the product(s).

Mid semester exam 20%, end of semester exam 50% (total theory component 70%)

Practical reports 20%, practical exam 5% (total practical component 25%)

Tutorials/active learning 5% (total tutorial component 5%)

Contact hours for on-campus students:

• Twenty four 1-hour lectures
• Six 1-hour tutorials
• Six 4-hour practicals

See also Unit timetable information

http://www.monash.edu/pharm/current/