BCH3042

Cell signal transduction: Role in cancer and human disease (6 points)

(SCI)

Leader: Dr Alfons Lawen

Offered:
Clayton Second semester 2003 (Day)
Clayton Second semester 2004 (Day)

Synopsis: This unit provides an advanced understanding of the molecular aspects of cell proliferation, cell signalling, differentiation and cell death as they relate to cell biology and medicine, in particular cancer. Themes include basic mechanisms of cell signalling involving cell receptors, gene expression, hormones and endocrine networks, and intracellular signalling cascade. These concepts are applied to cell growth, differentiation and cell death and how the involvement of the immune system is regulated in diseases, including auto-immune diseases, cancer (and its treatment) and the destruction of T-cells after human immunodeficiency virus (HIV) infection.

Assessment: Examination (2 x 2 hours): 65% + Mid-semester test: 10% + Evaluation of practicals: 20% + Research paper analysis: 15%

Contact Hours: Two 1-hour lectures and one 4-hour practical/ tutorial/ self-directed learning exercise per week

Prohibitions: BTH3746 + Recommended: BCH2011 and BCH2022, or BMS2021 and BMS2042, MOL2011 and MOL2022, BCH3011 and BCH3031