BRM5013 - Techniques in medical biotechnology: Imaging, iPS cells, cell and gene therapies - 2019

6 points, SCA Band 3, 0.125 EFTSL

Postgraduate - Unit

Refer to the specific census and withdrawal dates for the semester(s) in which this unit is offered.


Medicine, Nursing and Health Sciences

Chief examiner(s)

Professor Graham Lieschke


Edwina McGlinn
Chau Khuong

Unit guides



  • Second semester 2019 (On-campus)


Master of Biotechnology students only


This unit covers the fundamental techniques and approaches in regenerative medicine and medical biotechnology.

Students will learn underlying principles and key techniques such as: non-invasive cell and animal imaging methods, image analysis, cell reprogramming, genome editing methods and experimental model systems.

Students will gain hands-on experience with cutting edge imaging techniques and cell reprogramming.


Upon successful completion of this unit, students will be able to:

  1. Discriminate between imaging technologies used to image biological processes in living cells, tissues and whole organisms
  2. Perform in vivo imaging of cells, tissues and organisms
  3. Describe principles of genome editing technologies, and discuss current challenges and future prospects for the use of these technologies in gene and cell therapy
  4. Integrate knowledge of cell plasticity; cell reprogramming, lineage conversion and differentiation
  5. Demonstrate proficiency in cell reprogramming, microscopy and immunofluorescence techniques
  6. Summarise the derivation and characterisation of mouse and human iPS cells


  • Group oral presentation (30 minutes) (20%)
  • Critical review and reflective journal (1,500 words each) (40%) (hurdle)
  • Workshop/ practical preparation and participation (40%) (hurdle)

Workload requirements

4 contact hours (2 hours seminars and 2 hours practical/ workshop

8 hours of private study (expected to be spent on assignments, and designated pre-class and post-class online learning activities to prepare for classes and consolidate knowledge.

See also Unit timetable information

This unit applies to the following area(s) of study