BMC2021

Synthetic Chemistry A ( 6 points, SCA Band 2, 0.125 EFTSL)

Leader: Professor Peter Scammells

Offered:
Parkville First semester 2005 (Day)

Synopsis: Synthetic Chemistry A lays a foundation of knowledge about the structure and reactivity of the key functional groups found in pharmaceuticals. Participants in this unit will also be introduced to the art of designing and performing multi-step syntheses of bioactive compounds. Knowledge in this area will be further extended in the semester two unit, Synthetic Chemistry B.

Objectives: At the completion of this unit the participant will: - Have detailed knowledge of the structure and properties of the common functional groups contained in pharmaceuticals. - Be able to name organic molecules according to IUPAC nomenclature. - Understand the reactivity of these functional groups. - Understand basic reaction to mechanisms. - Understand basic reaction kinetics and thermodynamics relevant to organic synthesis. - Have the practical ability to perform a basic synthetic step. - Have the practical ability to isolate and purify reaction products.

Assessment: Examination: 50% (2 hours); Mid-Semester Test (1 Hour) 20%; Practical Work 30%;

Contact Hours: The unit includes 12 weeks of 2 Lectures per week, 1 week of 1 Lecture / 1 Tutorial, as well as 9 x 4hr Practicals.

Prerequisites: CHM1011 Chemistry, CHM1022 Chemistry, BMC1021 Introduction to Medicinal Chemistry.

Corequisites: BMC2032 Biomolecules (Structure & Function), BMC2042 Analytical Methods, BMC2071 Toxicology, BMC2050 Computational Chemistry, BMC2080 Intro to Spectroscopy and BMC2101 Drug Formulation and Delivery.