CHM3922 - Advanced organic chemistry - 2017

A description of the advanced tools and methodologies that are used in the determination of reaction mechanisms will be provided. This is supported by a discussion of the theoretical basis of the design of synthetic pathways for target e.g. bioactive molecules. The knowledge gained will be used to elucidate the reaction mechanisms of common organic reactions and metal-mediated reactions towards identifying scope in organic chemistry. The development of chemical methods that allow realisation of the concept of a sustainable future will also be discussed. Advanced NMR spectroscopy will also be introduced as a useful tool to elucidating structure.

On completion of this unit students will be able to:

1. Identify and operate standard chemical laboratory apparatus to undertake and analyse routine organic transformations;
2. Identify and design strategies that exploit conjugate addition reactions;
3. Understand the rationale behind the design of strategies to assemble complex aromatic materials;
4. Identify and describe common pericyclic reactions;
5. Identify and understand routine transition metal catalysed and organocatalytic chemical reactions.

Examination (2 hours): 47% + Mid-semester test (1 hour): 23% + Laboratory work and short laboratory reports: 30%

To pass this unit a student must achieve a minimum score of 50% in the laboratory practical component and a minimum of 30% for the end-of-semester exam.

Three 1-hour lectures/tutorials and the equivalent of 3 hours of laboratory activity per week

See also Unit timetable information

Associate Professor Katya Pas

Chemistry

Medicinal chemistry

CHM2911. Students without this should consult the third year coordinator.