VCP3031

Pharmaceutics II A ( 3 points, SCA Band 2, 0.063 EFTSL)

Leader: Ms May Admans

Offered:
Parkville First semester 2006 (Day)

Synopsis: Drug metabolism. IV infusion and multiple dosing. Haemodialysis and modified release formulation. Drug pharmacokinetics in hepatic and renal failure. Protein binding and drug pharmacokinetics. Pharmaceutical and pharmacokinetic calculations.

Objectives: Students will develop an: - Understanding of the use of pharmacokinetics to direct the appropriate administration of drugs, particularly intravenous infusions and multiple dose administrations. - Appreciation of the impact of modified release oral and parenteral formulations on the pharmacokinetics of drugs, and of the impact of haemodialysis on drug therapy. - Understanding of drug metabolism, in general, focussing on clinical relevance. - Understanding of hepatic and renal elimination of drugs and the change to drug pharmacokinetics observed in hepatic and renal failure. - Ability in the areas of performing pharmaceutical and pharmacokinetic calculations.

Assessment: Written examination: 100% (2 hours). Satisfactory performance in practical work is required.

Contact Hours: 17 Lectures; Practicals / Workshops 4 x 3hrs including on-line delivery. Successful completion of this unit will require participants to allocate an average of 3 hours per week for 12 weeks (a total of 36 hours per study period).

Prerequisites: All 2nd year Bachelor of Pharmacy units