BCH3031

Advanced molecular biology: modern concepts and applications

(SCI)

Associate Professor Rod Devenish and Dr Kaye Trembath (Biochemistry and Molecular Biology)

6 points + Two 1-hour lectures and one 4-hour practical/ tutorial/ self-directed learning exercise per week + First semester + Clayton + Prerequisites: MOL2011 and MOL2022 + Highly recommended: BCH2011 and BCH2022 + Prohibition: BTH3757

Synopsis: The aim of this course is to provide an understanding of DNA as the genetic component of organisms and cells, encompassing the information content, the organisation of DNA sequences, and expression of this information into RNA and proteins. Topics include global aspects of genome organisation and expression outcomes (genomics and proteomics, respectively). Analytical methods enabling comparisons between different organisms and between multiple cells of an individual organism differentially expressing the same genome are considered. Other themes involve the development of multi-cellular organisms and the molecular diagnosis and treatment of human genetic disease.

Assessment: Examination (3 hours): 55% + Essay (2000 words): 15% + Evaluation of practicals and syndicate sessions/ data assessment/ oral presentations (30%) will take place weekly during the semester in the practical/ tutorial/ self-directed learning sessions