BCH3011

Biomolecules and technology

(SCI)

Dr Wayne Comper

12 points + Four 1-hour lectures, one 6-hour practical and one 1-hour tutorial per week + First semester + Clayton + Prerequisites: BCH2011 and BCH2022 + Prohibition: BCH3031 or BTH3757

Synopsis: Topics include gene structure, expression and regulation; macromolecular structure and interaction in relation to biological activity, focussing on protein structure in relation to function and evolution, regulation of enzyme activity, the extracellular matrix, and dynamic interactions of proteins; biotechnology including the use of immobilised enzymes as biocatalysts and biosensors, and the production of therapeutic proteins; recombinant DNA technology and genetic engineering; the molecular biology of genetic disease and its treatment including the development of gene therapy.

Assessment: Examinations (2 x 2 hours): 80% + Laboratory: 20%