BCH3011

Biomolecules and technology

Dr Wayne Comper

12 points
* Four 1-hour lectures, one 6-hour practical and one 1-hour tutorial per week
* First semester
* Clayton
* Prerequisites: BCH2011 and BCH2022
* Prohibition: BCH3031

Objectives On completion of this subject students should understand the molecular biology of gene structure, expression and regulation at a detailed level; comprehend macromolecular structure and function and cell-matrix interactions; achieve a broad view of the importance of biochemistry and molecular biology to current advances in biology, biotechnology, medicine and agriculture; develop skills in the use of routine biochemistry laboratory equipment and in advanced biochemical and molecular biological techniques; manipulate and interpret biochemical data; develop skills in the communication of scientific information by verbal and written means and by poster displays.

Synopsis This subject is presented in four main themes: (i) molecular biology - gene structure, expression and regulation together with aspects of molecular virology; (ii) macromolecular structure and interaction in relation to biological activity - details of protein structure in relation to evolution, regulation of enzyme activity, the extracellular matrix, and dynamic interactions of proteins; (iii) biotechnology - the use of immobilised enzymes, recombinant DNA technology and genetic engineering; (iv) genetic disease - the molecular biology of genetic disease and gene therapy. Practical training extends the student's skill in modern and advanced techniques in biochemistry and molecular biology.

Assessment Examinations (2x2 hours): 80%
* Laboratory: 20%

Prescribed texts

Alberts B and others Molecular biology of the cell 3rd edn, Garland, 1994