MPH2037

Measurement in clinical research

Dr R Buchbinder

2 hours per week over 14 weeks

Synopsis The subject aims to enable students to identify measures that will provide the best estimates of the effects of intervention and other variables in clinical research. An overview of measures and issues in clinical research; sampling and inference; selecting items, reducing items and creating aggregate scores; inter-rater and intra-rater reliability; reliability and interval consistency of responses; assessing the validity of measures; responsiveness of measures to significant clinical change; strategies for gathering data; wording of questions and design of response categories; data entry and management and handling of missing data will be covered in this subject.

Assessment Assignment and oral presentation

Prescribed texts

Streiner D L and Norman G R Health measurement scales: A practical guide to their development and use OUP, 1995
Kelsey J L, Thompson W D and Evans A S Methods in observational epidemiology OUP, 1986
Monographs in epidemiology and biostatistics vol. 10
Feinstein A R Clinimetrics Yale U P, 1987