MTE4539

Biomaterials

3 points
* 25 lectures, tutorials and practical classes
* Clayton

Objectives To obtain a knowledge of the environment in which biomaterials are used and reactions that occur between the implant and the environment, which leads to an understanding of the range of materials and devices that can be successfully implanted into the body.

Synopsis A brief history of the development and use of biomaterials with emphasis on the rapid increase in use of biomaterials over the last three decades. The body environment and biocompatibility. The effects of implants on tissues and the effects of tissues on implants. Biocompatible materials - metals, ceramics, polymers and composites. Properties of bone. Materials selection, design, performance and degradation using the following examples - fracture fixation devices (plates, screws, nails etc.), synovial joint replacements (hip, knee, shoulder etc.), teeth (amalgam restorations, bridges, dentures, orthodontic materials etc.). Soft tissue replacement and implants. Tissue- polymer interactions. Materials selection, design, performance and degradation using the following examples: arteries, heart valves, ligaments, tendons etc. Materials connected to the body - artificial hearts, mechanical circulatory assist devices, heart-lung machines, artificial kidneys etc. The monitoring of biomaterials in vivo.