Faculty of Pharmacy and Pharmaceutical Sciences

Monash University

Undergraduate - Unit

This unit entry is for students who completed this unit in 2015 only. For students planning to study the unit, please refer to the unit indexes in the the current edition of the Handbook. If you have any queries contact the managing faculty for your course or area of study.

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6 points, SCA Band 2, 0.125 EFTSL

Refer to the specific census and withdrawal dates for the semester(s) in which this unit is offered.

FacultyFaculty of Pharmacy and Pharmaceutical Sciences
OfferedParkville First semester 2015 (Day)
Coordinator(s)Dr Bernard Flynn


Previous title Synthetic Medicinal Chemistry


The principle aim of this subject is to provide students with a detailed knowledge of numerous aspects of synthetic organic chemistry, as it applies to modern medicinal chemistry.

The subject follows from PSC2021 and PSC2122, covering advanced organic synthesis and methodology. Topics include catalysis in synthesis, radical chemistry, organometallic chemistry, heterocyclic chemistry, reactive intermediates and stereochemistry, as well as retrosynthetic analysis. An understanding of reaction mechanisms will be emphasized throughout. The practical component reinforces aspects of the lecture course with laboratory experience.

This will involve:

  • catalysis and biocatalysis
  • organometallic reactions
  • radical reactions
  • heterocyclic chemistry
  • asymmetric synthesis
  • reactive Intermediates


At the end of this unit students will be able to demonstrate:

  1. A wider knowledge of synthetic methodology;
  2. A knowledge of the use of catalysis in synthetic chemistry;
  3. An understanding of radical reactions and their role in synthesis;
  4. A broader knowledge of organometallic and heterocyclic chemistry;
  5. The ability to undertake a retrosynthetic analysis and to design a synthesis of a target molecule;
  6. The ability to read and understand the synthetic organic chemistry literature;
  7. The practical ability to perform a routine synthesis in the laboratory and experience of most common operations in a synthetic chemistry laboratory.


Final exam (2.5 hour): 60%; mid-semester exam: 10%; practical assessments: 20%; practical exam: 10%.

Workload requirements

Contact hours for on-campus students:

  • Twenty 1-hour lectures
  • Nine 4-hour laboratory practical exercises, including practical exam

Additional requirements:

  • Twelve hours practical report preparation

See also Unit timetable information

Chief examiner(s)


PSC2021 Structural Organic Chemistry
PSC2122 Synthetic Organic Chemistry

Additional information on this unit is available from the faculty at: