Faculty of Science

Monash University

Undergraduate - Unit

This unit entry is for students who completed this unit in 2015 only. For students planning to study the unit, please refer to the unit indexes in the the current edition of the Handbook. If you have any queries contact the managing faculty for your course or area of study.

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6 points, SCA Band 2, 0.125 EFTSL

Refer to the specific census and withdrawal dates for the semester(s) in which this unit is offered.

FacultyFaculty of Science
OfferedGippsland Second semester 2015 (Day)
Gippsland Second semester 2015 (Off-campus)
Coordinator(s)Dr Barbie Panther


In this unit students will study the structure, synthesis, relativity and analysis of simple organic molecules with a focus on pharmaceuticals and biochemicals. Specific topics will include reactive intermediates, molecular rearrangements, elimination reactions, nucleophilic substitution, aromatic and heterocyclic chemistry, carbonyl compounds and metalloproteins. The experimental program will emphasise the synthesis of pharmaceuticals and the use of spectroscopic and chromatographic methods of analysis.


On completion of this unit students will be able to:

  1. Discuss the reactivity of various functional groups and write equations for these reactions;

  1. Suggest reaction pathways for the synthesis of simple organic molecules from readily available materials and write reactions for these pathways;

  1. Describe the mechanisms of SN1, SN2, E1 and E2 reactions and predict the conditions which favour these reactions;

  1. Write reaction pathways, and suggest favourable conditions, for the synthesis of simple pharmaceuticals;

  1. Explain the principles of Infrared, Mass Spectrometry and Nuclear Magnetic Resonance spectrometry and determine the structure of organic and organometallic molecules using these methods;

  1. Synthesise organic compounds in the laboratory and use analytical instruments to determine the purity and structure of synthesised products.


Six assignments (500 words each): 20%
Practical work: 25%
Examination (3 hours): 55%

Workload requirements

Three 1-hour lectures and an average of three hours of laboratory per week

See also Unit timetable information

Chief examiner(s)

This unit applies to the following area(s) of study


CHM1011, CHM1051, CHM1022, CHM1052 or equivalent