Monash University Handbook 2011 Undergraduate - Unit

Refer to the specific census and withdrawal dates for the semester(s) in which this unit is offered.

Synopsis

Applied analytical methods aims to provide the student with an understanding of the analytical method development and validation specifically for hand contamination and industrial application and implication of product stability.

This will involve:

• HPLC principles
• associated equipment
• method development
• method validation
• troubleshooting

Objectives

At the end of this unit students will be able to:

Knowledge and comprehension of principles of chromatography

1. Demonstrate preparation of mobile phases, stock and std solutions
2. Ability to plumb HPLC systems, troubleshoot common problems
3. Create and utilise calibration plots (weighting data)
4. Formulate an approach to method development
5. Generate and evaluate method validation data
6. Method transfer between HPLC and UPLC
7. Use HPLC methodologies in drug dissolution testing of tablets manufactured in PSC3201

Assessment

final exam: 60%; practical work: 30%; tutorial work: 10%

Chief examiner(s)

Dr Laurence Orlando
Dr Michelle McIntosh

Contact hours

3 hours lecture; 24 hours of tutorias; and 44 hours of practicals

Additional information on this unit is available from the faculty at:

http://www.monash.edu.au/muso/support/