PHA3052

Poisons and toxins ( 6 points, SCA Band 2, 0.125 EFTSL)

Leader: Assoc Prof Roger King and Dr Elizabeth Davis

Offered:
Clayton T3-58 2005 (Day)

Synopsis: Introduction and history of toxicology. Clinical and forensic toxicology. Basis of selective toxicity and mechanisms underlying the development of resistance. Mechanisms of action and exposure to chemical agents as a cause of acute and chronic illness. Occupational exposure to chemicals. Public health aspects, and the regulation, of chemicals in the environment and foods. Development of standards and regulations. Chemical warfare. The mechanism of action of animal venoms and plant toxins.

Objectives: On completion of this unit, students will: demonstrate an understanding of the terminology used in the fields of toxicology and toxinology; be able to explain the basis of selective toxicity and the toxic effects of drugs and chemicals; be able to explain the mechanism of action of toxins present in plants and venomous animals, have developed the skills required to critically evaluate toxicological data, have enhanced the skills required to obtain and evaluate scientific data and literature, have enhanced the skills required to work effectively in a team environment, have gained some understanding of the design, performance and evaluation of experiments to determine the mode of action of animal venoms.

Assessment: Written tests: 60% + Presentation and written assignment: 25% + Practical exercises: 15%

Contact Hours: Four 1-hour lectures and three hours of laboratory or self-directed learning/ tutorial per week in weeks 7-12

Prerequisites: PHA3011 and PHA3021