GEN3041

Genomics and Molecular Genetics ( 6 points, SCA Band 2, 0.125 EFTSL)

Leader: Professor John Hamill

Offered:
Malaysia First semester 2005 (Day)

Synopsis: Structural components of genomes, ranging from unicellular to multicellular organisms, including humans, are examined and mechanisms controlling gene expression in response to environmental stimuli are examined in detail. Ongoing developments in the rapidly advancing field of genomics will be introduced to provide a basic understanding of the various sub components of this field (for example human genomics, comparative genomics, functional genomics). Students will acquire basic laboratory skills involving advanced techniques in molecular genetics and genomic analysis and also experience in computer assisted genetic analysis, database examinations and bioinformatic inquiry

Objectives: Genomics and Molecular Genetics provides a framework whereby students can appreciate the fundamental aspects of this unit area; its interdisciplinary nature and its universality and the practical applications of this knowledge in industry, agriculture and human welfare. Upon completion, students will have gained a solid understanding of the structure of genomes, with the focus on eukaryotic genomes, ranging from simple unicellular organisms such as yeast and protozoans to complex, multicellular organisms, including humans. Students will also gain a thorough understanding of the molecular processes that govern gene expression in these organisms in response to a variety of interacting environmental and developmental cues. Ongoing developments in the rapidly advancing field of genomics will be introduced to provide a basic understanding of the various sub components of this field (for example human genomics, comparative genomics, functional genomics, agricultural genomics, developmental genomics). Students will acquire basic laboratory skills involving advanced techniques in molecular genetics and genomic analysis and also experience in computer assisted genetic analysis, database examinations and bioinformatic inquiry.

Assessment: End of semester written examination: 50% + Practical exercise reports and problem solving exercises: 35% + Assignment (critical literature review and/or database analysis, 2000 words): 15%

Contact Hours: Two 1-hour lectures; one 3-hour practical exercises or computer database analysis session

Prerequisites: GEN2041 and at least 12 points from GEN2052, BTH2746, BTH2757 and MIC2011 + Recommended: GEN2041 and GEN2052, and BTH3757 (as a complimentary unit)