BCH2022

Metabolic basis of human diseases ( 6 points, SCA Band 2, 0.125 EFTSL)

Leader: Dr Alfons Lawen

Offered:
Clayton Second semester 2005 (Day)

Synopsis: A general outline of cellular metabolism is provided. The material presented will illustrate normal metabolic pathways and their dysfunction in various human diseases and conditions including diabetes, alcoholism, starvation, glycogen storage diseases and juvenile developmental problems. The biochemical basis of hormonal regulation and nutrition, in both famine and disease, is presented.

Objectives: On completion of this unit, students will have a basic understanding of the principals of utilisation of energy by mammalian organisms; the biosynthesis and breakdown of major biological molecules; the cellular metabolism and the regulation and integration of metabolic processes in tissues; and the biochemical basis of nutrition. The specific objectives of the small group teaching and practical exercise program will enable students to develop problem-solving skills through the evaluation of biochemical data, to develop skills in the presentation of data and scientific ideas both verbally and in writing and to have an understanding and hands-on experience of the basic principles of the measurement of biological molecules in the context of cellular metabolism.

Assessment: Mid-semester test (45 min): 10% + Examinations (2 x 2 hours): 30% each + Evaluation of practicals/assignments/case studies: 30%

Contact Hours: Three 1-hour lectures and 3-hour practical/tutorial/self-directed learning exercise per week

Prohibitions: BTH2757, BMS2021 + Recommended: BCH2011