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Chemistry of Bioactive Compounds (6 points)


Leader: Dr Peter Junk

Clayton Second semester 2003 (Day)

Synopsis: This subject is approached first by an introduction to the discovery, isolation and identification of naturally occurring bioactive molecules. This is followed by a discussion of the theoretical basis of the design of synthetic pathways for target bioactive molecules. Selected practical examples are then treated using the principles learned. This then leads on to a description of the application of modern organometallic reagents in sythesis. Finally the synthesis, structure and reactivity of bioinorganic compounds, many of which have been designed to mimic Nature's armoury of molecules and catalysts, are examined.

Assessment: One 2-hour examination: 50% + Assignments and computer testing: 20% + Laboratory work and short laboratory reports and proforma reports: 30%

Contact Hours: Two 1-hour lectures, one 1-hour tutorial and the equivalent of 3 hours of laboratory activity per week

Prerequisites: 12 points of level-one chemistry and normally CHM2911 or CHM2912 or CHM2942 and 6 other points of level-two chemistry, students without these should consult the coordinator

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