BMS3021

Molecular medicine and biotechnology

(MED)

Professor P Nagley (Biochemistry and Molecular Biology)

6 points + 3 lectures per week and 3 hours practical or equivalent + First semester + Clayton + Prerequisites: BMS2021 and BMS2042

Synopsis: This subject will provide an introduction into the molecular mechanisms that mediate human diseases and the specific biotechnologies used to facilitate diagnosis and treatment. The disease mechanisms mediated by genetic disorders resulting in abnormalities in protein folding, protein trafficking and gain or loss of protein function will be presented. State of the art developments in molecular medicine including transgenic models of human disease, gene therapy, and recent developments in transplantation will be highlighted. Specific biotechnologies to be discussed include structure-based drug design, production of recombinant proteins, vaccine technology and research commercialization.

Assessment: Examination: Mid semester (1 hour): 10% and final (3 hours): 50% + Problem-based exercises: 15% + Literature review: 10% + Student's research performance: 15%