BCH3022

Cellular organisation: Organelle structure and function in health and disease

(SCI)

Dr Wayne Comper (Biochemistry and Molecular Biology)

6 points + Two 1-hour lectures and one 4-hour practical/ tutorial/ self-directed learning exercise per week + Second semester + Clayton + Prerequisites: BCH2011 and BCH2022 + Recommended: BCH3011 and BCH3031 + Prohibition: BTH3746

Synopsis: The aim of this course is to provide an advanced understanding of the structure-function of the individual structural organelles and components of the cell in the context of cell biology and disease processes. Topics include the cytoskeleton, the formation of the membranes, the intra-cellular trafficking of proteins, the cellular internalization/export of proteins. Over-riding themes of this subject are: (1) to view the cell as a dynamic unit composed of a series of interacting organelles; and (2) to understand the cell as a semi-independent biological entity in constant contact and communication with the extracellular environment and with other cells in multi-cellular organisms.

Assessment: One examination (2 hours): 65% + Evaluation of practicals and syndicate sessions/ data assessment/ oral presentations undertaken in the weekly practical/ tutorial/ self-directed learning sessions: 35%