PHA3011

Principles of drug action

(SCI)

Dr Wayne Hodgson

6 points + Four 1-hour lectures and three hours of laboratory or self-directed learning/ tutorial per week + Weeks 1-6 First semester + Clayton + Prerequisites: Two of PHA2022, PHY2011, PHY2021 or PHY2032 or BMS2031 + Corequisite: PHA3021

Synopsis: Principles of drug action - drug receptor interactions, receptors, signalling pathways, enzymes, ion channels, neurotransmitter mechanisms; mediators including histamine, 5HT, eicosanoids, peptides including renin angiotensin system, endothelial derived factors; pharmacokinetic principles, drug absorption, drug distribution, pharmacokinetics and drug metabolism. Data acquisition, analysis and interpretation.

Assessment: Examination (2 hours): 60% + Written assignment (1000 words): 20% + Laboratory work and practical test: 20%