GEN3031

Genetics of development

(SCI)

Professor David Smyth

6 points + 5 hours per week (2 hours lectures, 3 hours practicals/tutorials/discussion groups) + Clayton + First semester + Prerequisites: 12 points from second level GEN, MOL, BOT and ZOO or BMS2021 and BMS2042 + Strongly recommended: GEN2041 or BMS2042

Synopsis: This subject explores how genes control the unfolding of the body plan following fertilization, and genetic processes in tissue differentiation. A comparative approach is used, based on model organisms including yeast, Arabidopsis, a nematode, a fly and the mouse. The impact of genome sequence projects is highlighted. Implications for medicine (e.g. birth defects, tissue replacement) and animal and plant production (e.g. genetically modified organisms) will be fully explored. Experience in modern molecular and cytological techniques is offered.

Assessment: Examination (3 hours): 50% + Practical reports: 25% + Oral presentation: 10% + Written assignment (2,000 words): 15%