MPH1028

Toxicology I

(MED)

Professor J McNeil and Dr D Goddard

1.5 hours per week over 14 weeks plus tutorials

Synopsis: Principles of toxicokinetics, the more common types of adverse effects of substances and the typical tests used to elicit these effects. Mechanisms of toxicity, dose-response relationships, patterns of organ toxicity, acute and chronic toxicity tests, no-observed-effect levels, extrapolation of animal results to humans, genotoxicity, reproductive toxicology, neurobehavioural toxicology, immunotoxicology, measures of risk and risk perception, analytical techniques, and planning for toxicological emergencies.

Assessment: Assignment + Multiple-choice examination