MED1011

Principles of biochemistry

(MED)

Dr M-P Van Damme (Biochemistry and Molecular Biology)

Synopsis: The nature of biological molecules and importance of water in cellular biology. The primary, secondary, tertiary and quaternary structures of proteins and how these determine biological function. Enzyme-catalysed reactions, kinetic analysis of enzyme activity, enzyme inhibition and regulation. Biophysical principles involved in metabolic pathways, importance of ATP in cellular metabolism. The generation of ATP from acetyl CoA via electron transport chain and tricarboxylic acid cycle and the nature and role of carbohydrates and lipids in energy metabolism of the cell.

Assessment: End-of-semester examination (3 hrs): 90% + Small group teaching: 10%