DIM1201

Immune Regulation: Theory and Applied

(MED)

Dr Jennifer Rolland

24 points + 10 hours per week (2 lectures, 2 hour tutorial, 6 hour practical) + Second semester + Alfred

Synopsis: The selection of B cells and the generation of B cell heterogeneity will be discussed. The role of the thymus in the development of T lymphocyte repertoires will also be reviewed as will mechanisms of immunoregulation, including tolerance to self antigens, regulation of immune responses by cytokines, and manipulation of the immune response by drug treatment. Practical classes will cover principles of molecular and cellular immunology including PCR as well as techniques for measuring cytokine production, cell cytotoxocity and B cell function. In addition, students will be placed in research laboratories within the department for the purpose of gaining project-based laboratory experience.

Assessment: Theory examinations: 25% + Oral presentations: 10% + Two essays (2000 words each): 15% + Practical class reports: 25% + Project report: 25%