Surgery
Head:
Professor P E O'Brien
Address: Department of Surgery, Alfred Hospital, Commercial Road,
Prahran 3181
Telephone: (03) 9276 2608
Fax: (03) 9510 3365
Email: paul.obrien@med.monash.edu.au
- Colorectal cancer Prevention of experimental colorectal cancer
using NSAIDs and other chemo-preventive agents; determination of mechanisms for
NSAID prevention; characterisation of colorectal tumours, growth factors and
inhibitors, COX-1 and COX-2 expression in colonic tumours, aberrant crypt
studies; apoptosis.
- Liver metastases Characterisation of liver metastases from
colorectal cancer in the experimental model; microvascular structure and
angiogenesis; influence of growth and inhibitory factors; clinical studies of
treatment of colorectal cancer with particular emphasis on the use of Nd-Yag
laser for local tumour destruction.
- Ulceration and repair in the gastrointestinal tract Studies of
the process of healing of experimental gastric ulcers; the effect of age on the
development and healing of ulcers and the influence of NSAIDs on the process.
COX-1 and COX-2 expression studies in gastric ulcers; angiogenesis,
microvascular density studies; gastric ulcer healing and NSAIDs in the young
and aged rats; wound healing in vitro; apoptosis in ulcers;
chemo-prevention - NSAID therapy, gastrotoxicity effects.
- Skin Growth factors for keratinocyte culture optimisation;
effects of electric/magnetic fields on wound healing rate; autologous
chondrocytes for repair of articular cartilage in traumatised joints;
chrondrocyte culture - matrix antibody binding to bovine/human fibronectin.
- Obesity Clinical studies of the laparoscopic treatment of obesity
with the Lap Band. Consequences of weight loss on medical, physical and
psychosocial status.
- Cardiopulmonary transplantation and circulatory support
Improvement of methods of preserving the donor heart and lungs for
transplantation.
- The ageing heart and cardiac surgery Improving the understanding
of how the heart in the elderly patient tolerates open heart surgery.
Developing new treatments to protect the ageing heart during cardiac surgery
especially by the use of co-enzyme Q10.
Acting
head: Clinical Associate Professor D Scott
Address: Department of Surgery, Monash Medical Centre, 246 Clayton Road,
Clayton 3168
Telephone: (03) 9550 5500
Fax: (03) 9550 5495
Email: david.scott@med.monash.edu.au
- Transplantation Studies in tissue and organ transplantation -
Preservation studies involving kidney, heart, liver and pancreas; studies in
immuno-suppression in relation to organ transplantation and especially chronic
allograft rejection; analysis of human kidney transplantation and combined
kidney and pancreas transplantation results on follow-up data, correlating
donor and recipient details; analysis of experimental transplantation data
correlating structural, functional and experimental procedures; experimental
studies of donor management to improve organ quality.
- Microsurgical studies Composite flaps (bone, muscle and skin);
analysis of microsurgical techniques in relation to vascular grafts.
- Vascular surgery Studies of the outcome of endovascular
procedures including balloon angioplasty, stenting and endovascular grafts for
aneurysm control.
- Gastrointestinal surgery Studies in oesophageal motility
assessing pharmacological modification of oesophageal motility; studies in
anorectal function and physiology; studies of gastrointestinal haemorrhage and
portal hypertension; Studies in nutrition comparing the effects of intravenous
and enteral feeding.
- Surgical education Problem solving in clinical surgery; medical
student assessment and evaluation; assessment of audit and quality assurance in
clinical surgery.
- Medical imaging Quality control in medical imaging;
computer-aided medical education applied to medical imaging.
wwwdev@monash.edu.au
Tue Oct 6 02:34:14 EST 1998