RAD2031

Pharmacology

Objectives On successful completion of this subject students will be able to demonstrate an understanding of the fundamental concepts of pharmacology, pharmacokinetics and toxicology; explain the general principles, classification, structure and properties of contrast media. Appreciate the nature of the risks associated with contrast media; describe the prevention, treatment and support for contrast media reactions. Students will also appreciate the characteristics of other drugs used in the clinical setting, general and local anaesthesia and their implications for patient care during diagnostic imaging examinations.

Synopsis General principles of pharmacology Definitions and general concepts. Phases of drug action (pharmaceutic, pharmacokinetic and pharmacodynamic). Sites of drug actions. Binding. Concentration response curves, potency, efficacy. Pharmacokinetics Routes of drug administration. Absorption. Distribution. Elimination. Introduction to toxicology. Contrast media, general principles History, structure, properties and classification. Possible uses of X-ray contrast media. Contrast media product quality and its preservation in practice. Risks of contrast media. Prevention and treatment of contrast media reactions. Contrast media for magnetic resonance imaging and ultrasound. The properties, mechanism of action, routes of administration, pharmacokinetics, adverse effects and adverse interactions of general anaesthetics, neuromuscular blocking drugs, local anaesthetics, sedatives, drugs used for the treatment of anxiety and drugs used for modification of gastrointestinal activity to facilitate radiographic procedures.

Assessment Examination (2 hours): 75% · Assignment: 25%

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