Measurement in clinical research
Dr R Buchbinder
2 hours per week over 14 weeks
Synopsis The subject aims to enable students to identify measures that will provide the best estimates of the effects of intervention and other variables in clinical research. An overview of measures and issues in clinical research; sampling and inference; selecting items, reducing items and creating aggregate scores; inter-rater and intra-rater reliability; reliability and interval consistency of responses; assessing the validity of measures; responsiveness of measures to significant clinical change; strategies for gathering data; wording of questions and design of response categories; data entry and management and handling of missing data will be covered in this subject.
Assessment Assignment and oral presentation
Prescribed texts
Streiner D L and Norman G R Health measurement scales: A practical guide to their development and use Oxford University Press, 1995
Kelsey J L, Thompson W D and Evans A S Methods in observational epidemiology Oxford University Press, 1986
Monographs in epidemiology and biostatistics vol. 10
Feinstein A R Clinimetrics Yale University Press, 1987
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