MONASH UNIVERSITY FACULTY HANDBOOKS
Medicine Handbook 1996
Published by Monash University
Clayton, Victoria 3168, Australia
Authorised by Academic Registrar, April 1996
MED1011
Principles of biochemistry
Lecturer to be advised (Biochemistry and Molecular Biology)
Objectives The aim of this subject is to provide students with an
introduction to three fundamental topics of contemporary biochemistry. This
will allow students to achieve a basic knowledge for the units to be taught
later in the medical curriculum. The objectives of the lecture course are for
students to understand the structure and properties of molecules associated
with the life process; to comprehend the physical and biochemical properties of
proteins, especially enzymes; and to understand aspects of cellular metabolism
in terms of release of energy and dietary inputs. The objectives of the
practical/small-group teaching course are to allow students to extend and
complement material given in the lectures as well as to provide experience in
manual skills and problem solving.
Synopsis The nature of biological molecules and importance of water in
cellular biology. The primary, secondary, tertiary and quaternary structures of
proteins and how this determines biological function. Enzyme-catalysed
reactions, kinetic analysis of enzyme activity, enzyme inhibition and
regulation. Biophysical principles involved in metabolic pathways, importance
of ATP in cellular metabolism. The generation of ATP from acetyl CoA via
electron transport chain and tricarboxylic acid cycle and the nature and role
of carbohydrates and lipids in energy metabolism of the cell.
Assessment End-of-semester examination (2 hrs): 90% + Practical
class/small group teaching: 10%
Recommended texts
- Kleinsmith L J and Kish V M Principles of cell and molecular biology
Harper Collins, 1995
- Lehinger A L and others Principles of biochemistry 1st or 2nd edn,
Worth, 1982 or 1993
- Stryer L Biochemistry 2nd or 3rd edn, Freeman, 1981 or 1988
- Ward A Physics and chemistry for the health sciences Excell
Biomedical, 1991
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