Undergraduate - UnitPSC2122 - Synthetic organic chemistry

This unit entry is for students who completed this unit in 2014 only. For students planning to study the unit, please refer to the unit indexes in the the current edition of the Handbook. If you have any queries contact the managing faculty for your course or area of study.

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6 points, SCA Band 2, 0.125 EFTSL

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Level	Undergraduate
Faculty	Faculty of Pharmacy and Pharmaceutical Sciences
Offered	Parkville Second semester 2014 (Day)
Coordinator(s)	Associate Professor Bernard Flynn

Synopsis

This subject aims to provide students with an understanding of:

The use of functional groups in carbon-carbon and carbon-heteroatom bond formation;
The fundamentals of molecular orbitals in pericyclic reactions;
The preparation and use of organometallic in organic synthesis.The synthesis of organic molecules, including naturally occurring bioactives and other drug molecules.

This will involve:

functional group manipulation .The chemistry of organometallic reagents.
pericyclic chemistry
synthesis of heterocycles
reactions of aromatic heterocycles
synthesis of heterocyclic drugs

Outcomes

At the end of this unit students will be able to:

Draw mechanisms and rationalise the outcome of a range of functional group manipulations;
Rationalise the use of functional groups in organic synthesis;
Understand the use of organometallic reagents in synthesis and their reaction mechanisms;
Understand the role of molecular orbitals in pericyclic reactions Apply knowledge of organometallic, pericyclic and heterocyclic reactions to the design of synthetic routes for preparing simple organic compounds.