Undergraduate - UnitBCH3021 - Cellular organisation: Organelle structure and function in health and disease

This unit entry is for students who completed this unit in 2012 only. For students planning to study the unit, please refer to the unit indexes in the the current edition of the Handbook. If you have any queries contact the managing faculty for your course or area of study.

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6 points, SCA Band 0 (NATIONAL PRIORITY), 0.125 EFTSL

Refer to the specific census and withdrawal dates for the semester(s) in which this unit is offered, or view unit timetables.

Level	Undergraduate
Faculty	Faculty of Science
Offered	Clayton First semester 2012 (Day)
Coordinator(s)	Professor Phil Bird

Synopsis

This unit provides an advanced understanding of the structure-function of the individual structural organelles and components of the cell in the context of cell biology and disease processes. Topics include the cytoskeleton, the formation of the membranes, the intra-cellular trafficking of proteins, the cellular internalization/export of proteins. Over-riding themes of this subject are:

to view the cell as a dynamic unit composed of a series of interacting organelles; and
to understand the cell as a semi-independent biological entity in constant contact and communication with the extracellular environment and with other cells in multi-cellular organisms.

Outcomes

On completion of this unit students will understand the biochemistry and molecular biology of cellular membranes; achieve a detailed understanding of the structure and function of subcellular organelles including the nucleus, mitochondria, peroxisomes, endoplasmic reticulum and golgi, and lysosomes in health and disease; understand the various aspects of intracellular and extracellular vesicle trafficking; comprehend the basis of many types of molecular machines that exist in cell biology; achieve a broad view of the importance of the discipline to current advances in biology, biotechnology and medicine; develop skills in the use of routine and advanced biochemistry laboratory equipment, procedures and techniques; manipulate and interpret biochemical data; be able to source information in the scientific literature on particular topics related to the discipline; develop skills in the communication of scientific information associated with this discipline by verbal and written means and by poster displays.

Assessment

One examination (3 hours): 60%
Evaluation of practicals and syndicate sessions/data assessment/oral presentations undertaken in the weekly practical/tutorial/self-directed learning sessions: 30%
Evaluation of mentored literature review (essay): 10%

A pass in the practicals and syndicate sessions must be obtained to pass the unit. The essay must be submitted to pass the unit. If either of these requirements are not met, the student will be awarded, at maximum, 49N for the unit.