Monash University Handbook 2010 Undergraduate - Unit

Synopsis

An introduction to the major techniques which underpin the practical aspects of compound identification for medicinal chemistry: UV spectroscopy, IR spectroscopy, Mass spectroscopy and NMR spectroscopy.

Objectives

After completing this unit students will be expected to be able to:

1. Describe how spectroscopic techniques can be used in the process of identification of small drug like molecules.
2. Describe briefly the phenomena behind the spectroscopic techniques.
3. Analyse UV, IR, 1D NMR and Mass spectra of an unknown molecules and to use these to determine their structure.
4. Analyse 2D NMR spectra as a means to assign the NMR spectra of more complex molecules.
5. Demonstrate the correct reporting of spectroscopic data as used in medicinal chemistry.

Assessment

Final exam (3 hour): 60%; Mid-semester exam: 20%; Practical assessments: 20%.

Chief examiner(s)

Dr James Swarbrick

Contact hours

36 hours of lectures; 3 hours of tutorials; 7 hours computer aided learning; five 3 hour practical classes

Prerequisites

PSC1021 and PSC1022 or equivalent

Additional information on this unit is available from the faculty at:

http://www.monash.edu.au/muso/support/