Monash University Handbook 2010 Undergraduate - Unit

Synopsis

Synthetic Chemistry A lays a foundation of knowledge about the structure and reactivity of the key functional groups found in pharmaceuticals. Participants in this unit will also be introduced to the art of designing and performing multi-step syntheses of bioactive compounds. Knowledge in this area will be further extended in the semester two unit, Synthetic Chemistry B.

This will involve:

• Electrophilic addition reactions and stereochemistry
• Substitution and elimination reactions
• Aromatic compounds
• Carbonyl compounds
• Additional oxidation-reduction reactions and amines

Objectives

At the end of this unit the student will be expected to;

1. have a detailed knowledge the structure and properties of the common functional groups contained in pharmaceuticals
2. be able to name organic molecules according to IUPAC nomenclature
3. understand the reactivity of these functional groups
4. understand basic reaction mechanisms
5. understand basic reaction kinetics and thermodynamics relevant to organic synthesis
6. have the practical ability to perform a basic chemical reaction / synthetic step
7. have the practical ability to isolate and purify reaction products.

Assessment

Final exam: 50%; mid-semester exam: 20%; practical reports: 20%; practical exam: 10%.

Chief examiner(s)

Professor Peter Scammells

Contact hours

36 hours of lectures; nine 4 hour practical classes

Prerequisites

PSC1021 Organic Chemistry I
PSC1022 Organic Chemistry II

Additional information on this unit is available from the faculty at:

http://www.monash.edu.au/muso/support/