Offered
Parkville First semester 2008 (Day)
Synopsis
Drug metabolism. IV infusion and multiple dosing. Haemodialysis and modified release formulation. Drug pharmacokinetics in hepatic and renal failure. Protein binding and drug pharmacokinetics. Pharmaceutical and pharmacokinetic calculations.
Objectives
Students will develop an:
- Understanding of the use of pharmacokinetics to direct the appropriate administration of drugs, particularly intravenous infusions and multiple dose administrations.
- Appreciation of the impact of modified release oral and parenteral formulations on the pharmacokinetics of drugs, and of the impact of haemodialysis on drug therapy.
- Understanding of drug metabolism, in general, focussing on clinical relevance.
- Understanding of hepatic and renal elimination of drugs and the change to drug pharmacokinetics observed in hepatic and renal failure.
- Ability in the areas of performing pharmaceutical and pharmacokinetic calculations.
Assessment
Written examination: 100% (2 hours). Satisfactory performance in practical work is required.
Contact hours
17 Lectures; Practicals / Workshops 4 x 3hrs including on-line delivery.
Successful completion of this unit will require participants to allocate an average of 3 hours per week for 12 weeks (a total of 36 hours per study period).
Prerequisites
VCP2032
