Monash University Handbooks 2008

VCP3022 - Medicinal chemistry III B

3 points, SCA Band 2, 0.0625 EFTSL

Undergraduate Victorian College of Pharmacy

Leader: Dr Phil Thompson

Offered

Parkville Second semester 2008 (Day)

Synopsis

The aim of this unit is to build a chemically literate understanding of modern therapeutic agents, which allows students to appreciate the molecular basis for drug efficacy via interaction with macromolecular targets, pharmacokinetics and the role of stability, metabolism and transport as well as the molecular basis for drug side effects. We use four classes of drugs - CNS-active drugs for schizophrenia and Parkinson's Disease; Drugs for Diabetes Mellitus; Opioid analgesics and Steroid based drugs as current exemplars of drug design, discovery, development and application.

Objectives

1.Students will develop an understanding of the relationship between the chemical structure and biological activity of drugs and endogenous substances. Four topics are covered CNS-active drugs for schizophrenia and Parkinson's Disease; Drugs for Diabetes Mellitus; Opioid analgesics and Steroid based drugs as current exemplars of drug design, discovery, development and application

Assessment

The end of semester paper 80%

Contact hours

The course comprises 20 hours of lectures and 4 hours of tutorials.

Prerequisites

VCP2021 Medicinal chemistry IIA and VCP2022 Medicinal chemistry IIB

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