Leader: Dr Jalal Jazayeri

Offered

Parkville First semester 2008 (Day)

Synopsis

This unit lays a foundation of knowledge about mammalian systems and provides the relationship between pathophysiology and the rational design and use of drugs. Students will be introduced to the concepts underlying basic biochemistry and molecular biology of the cell, and will then consider in detail the structure and function of the musculoskeletal, nervous, endocrine and cardiovascular systems. One or more examples of disease states which are amenable to pharmacotherapy will be discussed in detail for each organ / system. Students will perform a number of tasks which will help with the development of critical thinking skills

Objectives

After completing this unit students will be expected to be able to:

1. Describe the functioning of a single cell, including the transcription / translation process, energy utilisation, and the role of the major classes of macromolecules.
2. Describe the structure of each major organ / organ system considered within the course.
3. Explain the function of each major organ / organ system considered within the course, with reference to the structure.
4. Explain the physiological basis for the most common disease states to affect each organ / organ system considered within the course.
5. Analyse simple examples of cellular and organ dysfunction, and be able to explain the likely consequences for the function of the system
6. Demonstrate the development of written communication skills appropriate for 1st year students - explain the pathophysiology for one disease state and one drug treatment associated, relating the drug target to the disease state.

Assessment

Examination (2.5 hours) 70%

Contact hours

72 hours