DEV3032 - Stem cells and regeneration

Leader: Professor John Bertram

Offered

Clayton Second semester 2008 (Day)

Synopsis

This unit begins with an introduction to stem cell biology and regenerative medicine. Characteristics, basic biology and methods for studying stem cells are then described. Then characteristics of stem cells in specific tissues are described, including haematopoeisis, the kidney, gut and nervous system. Finally, aspects of tissue engineering and use of stem cells in animal biotechnology are covered. Students also conduct a research project in a stem cell laboratory. Two moderated classroom discussion on commercialization and ethical issues of stem cell research are also included.

Objectives

On completion of this Unit students will be able to: describe the basic biology of stem cells; discuss key techniques in stem cell research; discuss the status of research into the identification and characterisation of stem cells; explain how stem cells are currently being used, and will likely be used, to regenerate diseased organs; describe how stem cells can be combined with factors and materials to engineer replacement tissues; be aware of some of the controversies surrounding stem cell research; have practical experience in stem cell research; and demonstrate critical and independent thinking, synthesis of the literature and scientific presentation.

Assessment

Mini-poster presentation on the laboratory placement research project: 20%
on-line practical class assessment: 10%
Written report on one of the issues covered by the moderated discussions: 10%
Final examination: 60%

Contact hours

Two lectures per week. 15 hours research placement in a stem cell research laboratory (over 7 weeks): Two x 3-hour moderated class discussions, One x 3-hour wet practical classes and Two x 3-hour IT-based practical class exercises.

Prerequisites

DEV2011, DEV2022 and MOL2011; or BMS1062, BMS2011, BMS2021 and BMS2031.