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Monash University

Monash institutes of research - Faculty of Medicine, Nursing and Health Sciences

The following section outlines major research areas in centres of the Monash Institute of Medical Research and the Monash Institute of Health Services Research.

Monash Institute of Medical Research

For details visit http://www.monashinstitute.org/research-centres.html

Centre for Reproduction and Development

Reproduction

  • Assisted reproduction; andrology; impotence; infertility; fertility; fertilisation; embryogenesis; male contraception; autoimmunity.

IVF

  • Gene expression in early embryos; cloning; reprogramming; activin and follistatin function.

Genetics of male infertility

  • Testis biology; germ cell transplantation; epididymal function; fertilization; immunocontraception; inflammation biology, stem cell isolation and characterization; cell-based therapies, transgene, Gene knockout; developmental biology.

Contact details

Professor Michael Holland: email michael.holland@med.monash.edu.au

Centre for Urological Research

  • Prostate; androgens; testosterone; oestrogen; prostate development; prostate disease; stem cells; benign prostatic hyperplasia; BPH; urinary tract disease.

Contact details

Professor Gail Risbridger: email gail.risbridger@med.monash.edu.au

Centre for Functional Genomics and Human Disease

  • Genetics; genetics of human disease; functional genomics; cancer; cell death; apoptosis; brain cell death; stroke; toxic shock; sepsis; Down's syndrome; Alzheimer's disease; SOCS1; inflammation tumour immunity; cytokine signalling; transcription factors; inflammatory diseases; molecular biology.

Contact details

Professor Paul Herzog: email paul.herzog@med.monash.edu.au

The Ritchie Centre for Baby Health Research

  • Premature babies; baby health; sleep studies; sleep disordered breathing; sleep apnoea; Melbourne Children's Sleep unit; foetal physiology; neonatal physiology; neonatal intensive care; sleep physiology; neonatal physiology; neonatal intensive care; sleep physiology and medicine; Monash Medical Centre Neonatal Unit; Neonatal neurological outcomes; sudden infant death syndrome (SIDS); lung growth and development.

Contact details

Contact: Professor Adrian Walker: email adrian.walker@med.monash.edu.au

Centre for Cancer Research

  • Protein kinase R (PKR; Wilms Tumor (neuroblastoma); RNA interference; Short interfering RNA; Innate immunity; bladder cancer; kidney cancer; diabetes and cancer; prostate cancer lymph node metastatsis.

Contact details

Professor Bryan Williams: email bryan.williams@med.monash.edu.au

Centre for Women's Health Research

  • Endometriosis; vascular biology; angiogenesis; vascular maturation; endometrial angiogenesis; endometrial cancer stem cells; endometrial epithelial and mesenchymal stem cells; miscarriage; in utero infection; endogenous opiods; amnion stem cells; intra-uterine infection; uterine fibroids.

Contact details

Professor Peter Rogers: email peter.rogers@med.monash.edu.au

Centre for Pain Medicine and Palliative Care

  • Holistic approach to treating pain and suffering in the community. This includes the emotional, social and financial impact on the patient, family and society.

Contact details:

Professor Colin Goodchild: email colin.goodchild@med.monash.edu.au

Monash Institute of Health Services Research

Major research areas fall within the following areas (designated by research centre within the Monash Institute of Health Services Research).

Australasian Cochrane Centre

  • Evaluation of practice change and outcomes of care; evidence use in systematic review; uptake of systematic review.

Centre for Clinical Effectiveness

  • Implementation of models of care to promote use of best evidence in various clinical settings; analysis of data and systems of care in relation to quality and safety of care; patient flow modelling using computer simulation models.

Monash Ageing Research Centre

  • Determinants of healthy aging; applied research in pain management in the elderly; interdisciplinary research in the elderly; dementia care; attitudes to ageing and the aged; movement disorders including Parkinson's disease; interventions for health ageing; chronic illness and ageing.

Jean Hailes Foundation Research Centre

  • Options for dealing with hormonal changes in midlife women; hormones and the cardiovascular system; healthy aging and health services research: women and health professionals; sociological perspectives on health; clinical trials on prevention of disease: obesity, PCOS, diabetes, CVD.

Turning Point Alcohol and Drug Research Centre

  • Epidemiological research and investigation of patterns of drug use and related consequences in the community.

Gender and Medicine

  • Gender and the clinical workforce; gender and cultural competence; gender competence in undergraduate and post-graduate curriculum.

Contact details

Associate Professor Damien Jolley: telephone +61 3 9594 7509; email damien.jolley@med.monash.edu.au or visit http://www.mihsr.monash.org/

Monash Immunology and Stem Cell Laboratories

The Monash Immunology and Stem Cell Laboratories (MISCL) harbours world renowned Monash research in stem cell science, with an emphasis on embryonic stem cells and their potential applications in the repair and regeneration of blood, pancreatic, respiratory, liver, reproductive, thymic, renal and neural tissues. Interests also include adult (mature) and placental stem cells, particularly in relation to lung, liver and kidney regeneration. There is also a focus on the immune system for treating cancer and for the induction of transplantation, tolerance, correction of autoimmunity and reversal of immunodeficiency.

Research Groups

  • Stem cells differentiation and development; immunology - stem cells - tolerance and thymic function; stem cell and tissue regeneration; neuroimmunology; Embryonic Stem Cell Differentiation Laboratory; adult stem cells in renal regeneration and repair

Contact details

Professor Graham Jenkin: telephone +61 3 9905 0775; email graham.jenkin@med.monash.edu.au or visit http://www.med.monash.edu.au/miscl/honours

Affiliated institutes

The following section outlines major research areas in institutes affiliated with the faculty. Note, although students may undertake their research at an affiliated institute they can only be enrolled through a department or an accredited academic unit of the faculty.

Baker Heart Research Institute

  • Hypertension; atherosclerosis; sympathetic nervous system; stress; heart failure; risk assessment; risk reduction; noradrenalin release; panic disorders; arrhythmias; phosphatidyl inositol turnover; Na+, Ca+ transport; growth factors; vascular hypertrophy; heart transplantation; myocardial metabolism; mitochondria; atrial naturetic peptide; medullipin; endothelin; lipoprotein receptors; angiotensin 1 receptors; mineralocorticoid receptors; glucocorticoid receptors; receptor antagonists; 11_DF hydroxysteroid dehydrogenase; pro-opiomelanocortin; ACTH; _DF-endorphin; angiotensin II; serotonin; dopamine; central antihypertensive drugs; pituitary; hypothalamus; metalloendopeptidases; renal innervation; von Willebrand factor; platelet adhesion; GMP-140; PECAM-1; thrombosis; angiogenesis; inflammation; gene regulation.

Contact details

Visit http://baker.edu.au

Macfarlane Burnet Institute for Medical Research and Public Health

  • Human immunodeficiency virus; hepatitis viruses; respiratory syncytial virus; rubella virus; influenza; rotavirus; malaria; immunology; cancer; breast cancer; epidemiology; public health and social research; communicable diseases; international health, education and community development projects in 25 countries in Asia, Africa and the Pacific.

Contact details

Visit http://www.med.monash.edu.au/medicine/alfred/research/macfarlane.html

Mental Health Research Institute

Psychoses and related disorders

  • Schizophrenia; bipolar mood disorder; delusions; clinic for treating auditory hallucinations (hearing voices); addiction and substance abuse; mechanisms of action and effects of antipsychotic medication; adjunctive treatments for psychoses; collaborative therapy; serotonin; dopamine; SNPs; GABA receptor; kainite receptor; apolipoporotein; E; estrogen.

Alzheimer's disease and neurodegeneration

  • Oxidative stress in neurological disorders; drug interventions against toxic effect of A-beta accumulation; amyloid precursor protein; metals in the brain; delusions in Alzheimer's disease; ocular motor testing for early signs of disease onset; Parkinson's disease.

Platforms

  • Neurochemistry; neurophysiology; psychopharmacology; genetics and proteomics; cognitive neuropsychiatry; cell biology; neuropathology; animal models for psychosis and neurodegeneration; phenotyping; neural tissues repository; clinical trials; cognitive testing and therapy.

Contact details

Visit http://www.mhri.edu.au

Prince Henry's Institute of Medical Research

  • Neuroendocrinology; molecular endocrinology; reproductive endocrinology; testicular physiology; ovarian physiology; tissue remodelling; menstruation; implantation; cardiovascular disease; endocrine cancers, particularly breast and ovarian cancers; infertility; menstrual disorders; reproductive medicine; menopause; and ageing.

Contact details

Dr Evan Simpson: telephone · 61 3 9594 4397; email evan.simpson@princehenrys.org or visit http://www.princehenrys.org

Monash Medical Centre

Centre for Inflammatory Diseases

  • Rheumatoid arthritis; macrophage migration inhibitory factor (MIF); inflammatory signal transduction; Lupus; Leukocyte trafficking; Leukocyte-endothelial interactions; glomerulonephritis (kidney disease); glomerular injury; innate immunity; Hepatitis; Spesis; Cystic fibrosis; asthma; coagulation and inflammation; PAR-2 interactions, PAR-2 signalling; atherosclerosis; autoimmunity; type 1 Diabetes.

Contact details

Professor Stephen Holdsworth: email stephen.holdsworth@med.monash.edu.au