Skip to content | Change text size

VCF3081 - Toxicology I

12 points, SCA Band 2, 0.250 EFTSL

Undergraduate Victorian College of Pharmacy

Leader: Dr. John Haynes


Parkville First semester 2007 (Day)


Basic pharmacological mechanisms. Absorption, transformation, distribution, metabolism, pharmacokinetics, bioavailability and pharmacodynamics of xenobiotics. Mechanisms of toxicological insult as well as effects of xenobiotics on the blood, skin, liver, kidneys and the immune, respiratory, nervous, cardiovascular, reproductive and endocrine systems. Carcinogenesis, pesticides, heavy metals, solvents, animal toxins, plant toxins and ecotoxicology


Students will develop an idea of general pharmacological principles and methods used in establishing pharmacological actions of xenobiotics. The specific objectives are to:
Identify how chemical mediators undergo absorption, metabolism and distribution across body compartments to access sites of action.
Learn the general principles of pharmacology and toxicology through application to major organ systems.
Utilize a pharmacological approach to establishing sites of drug and xenobiotic action


Examination (2 hours)


All of 2nd year B.Form. Sci units