PHA3032 - Neuro and endocrine pharmacology

Leader: Dr Richard Loiacono

Offered

Clayton Second semester 2007 (Day)

Synopsis

This unit provides an integrated understanding of how drugs affect neuronal and endocrine function. Four major areas are covered: major neurotransmitters within the brain, reproductive endocrinology, metabolism and disorders of pancreatic and thyroid function, mood and pain, and, neurodegenerative disorders. The focus is on mechanisms of action, use and side effects of drugs affecting a range of neuronal and endocrine functions and includes topics such as drugs used in anaesthesia and sedation, anxiety, depression, epilepsy, schizophrenia and psychoses, Parkinson's and Alzheimer's disease, reproduction and contraception, diabetes, thyroid function and metabolism and calcium homeostasis.

Objectives

On completion of this unit, students will: have a broad understanding of how drugs can affect the nervous and endocrine systems; have developed an understanding of how drugs can affect neurotransmission within the brain; understand the potential for tolerance, addiction and abuse of many drugs that affect the brain; understand the hazards and dangers associated with tolerance, addiction and abuse of many drugs that affect the brain; understand the mechanisms of action, uses, adverse effects and interactions of drugs acting on the nervous and endocrine systems; have developed an understanding of the molecular biological and genetic techniques being applied to understand neuropharmacology and endocrine pharmacology at the cellular level; have developed skills to critically evaluate the scientific literature in neuropharmacology and endocrine pharmacology; have some understanding of the design, performance, evaluation and reporting of experiments in neuropharmacology and endocrine pharmacology; have skills in obtaining and using scientific information to write and present reports and essays.

Assessment

Examination (2 hours): 50%
Written assignment: 20%
Laboratory work and written practical reports : 20%
Test (1 hour): 10%

Contact hours

Two 1-hour lectures and three hours of laboratory or self-directed learning/ tutorial per week

Prerequisites

PHA3011, PHA3021