BND2021 - Nutritional biochemistry

Leader: Dr Janet Macaulay (Biochemistry)

Offered

Clayton First semester 2007 (Day)

Synopsis

This unit aims to provide a basic understanding of the metabolism of macro and micronutrients and of the role of nutrition in influencing cell growth, cancer development, blood formation and gene function. Emphasis will be on clinical relevance, the integration of biochemical pathways and how this is modulated by dietary change, and on techniques used to assess both normal dietary requirements and nutrient deficiencies. Students will be introduced to biochemical mechanisms of energy expenditure and storage, including metabolic adaptation to periods of fasting or food intake.

Objectives

At the completion of the unit the students will have an understanding of:

1. substrate partitioning and mechanisms of energy expenditure and storage;
2. the metabolic role of the liver;
3. substrate metabolism in the fasted and fed state;
4. metabolism of nitrogenous compounds, digestible and non-digestible carbohydrates and lipids;
5. the role of micronutrients and concepts of nutrient balance;
6. nutritional influences on cell growth, differentiation, programmed cell death and the development of the cancerous cell;
7. nutritional influences on the development of blood cells, blood coagulation and fibrinolysis;
8. introductory concepts in the nutrient modulation of gene expression;
9. in tutorials: to develop students' skills in integrating and relating new knowledge in Nutritional biochemistry to situations which they may encounter in a clinical setting; also to develop skills in research for additional information on questions arising in this process; and
10. in practical classes: to develop students' skills in scientific observation, data presentation and analysis; to introduce students to the use of food composition databases and to develop skills in dietary analysis using computer based programs.

Assessment

Examination: 40%
Mid semester test: 10%
Essay: 10%
Small group activities: 40%

Contact hours

6 hours per week (lectures and tutorials)

Prerequisites

Completion of year 1 Bachelor of Nutrition and Dietetics

Prohibitions

BMS2021