Molecular biology of microorganisms
Dr Andrew Davidson
12 points * 10 hours per week - 4 x 1-hour lectures, 6 hours practical * First semester * Clayton * Prerequisites: MIC2011 and MIC2022
This advanced subject extends material covered in MIC2011 and MIC2022 especially in molecular aspects of bacteria and viruses such as molecular genetics, control of expression, intracellular transport and secretion of macromolecules, recombinant DNA technology with bacterial plasmids and its applications. The great diversity and special features of virus replication and gene expression in eukaryotic cells are defined and considered in relation to the role of viruses as vectors in genetic engineering and in infectious disease.
Assessment
Written (2000 words): 10% * Examinations (3 hours): 55% * Practical work/Laboratory work: 35%
Prescribed texts
Brock T D and others Biology of microorganisms 7th edn, Prentice-Hall, 1994
Cann A J Principles of molecular virology Academic Press, 1993
Recommended texts
Davis B D and others Microbiology 4th edn, Lippincott, 1990
Fields B N Human virology OUP
Lewin B Genes 5th edn, OUP, 1994
Matthews R E F Plant virology 3rd edn, Academic Press, 1991
Watson J D Recombinant DNA Scientific American, Freeman, 1992
Watson J D and others Molecular biology of the gene vol. 1, 4th edn, Benjamin-Cummings, 1987