Molecular, developmental and applied genetics
Dr David Smyth
12 points * 10 hours per week * First semester * Clayton * Prerequisites: GEN2022
This subject is focused on recent advances in molecular genetics and genetic engineering. Topics covered include genome architecture of prokaryotes and eukaryotes, the molecular biology of bacteria, methods of DNA and gene manipulation and the analysis of gene structure and function during development. The applications of genetics in medical, agricultural and industrial biotechnology are emphasised. Practicals are designed to complement lecture material and will provide students with experience in recombinant DNA techniques, DNA sequencing and methods for studying gene expression after introduction of foreign genetic material into the genomes of higher eukaryotes.
Assessment
Written (2500 words): 15% * Examinations (3 hours): 50% * Practical work: 35%
Prescribed texts
Old R W and Primrose S B Principles of gene manipulation 5th edn, Blackwell, 1994
Recommended texts
Alberts B and others Molecular biology of the cell 3rd edn, Garland, 1994
Grierson D and Covey S Plant molecular biology 2nd edn, Blackie, 1988
Kung S and Wu R Transgenic plants vol. 1, Engineering and utilisation, Academic Press, 1993
Larrick J W and Burck K L Gene therapy: Applications of molecular biology Elsevier, 1991
Watson J D and others Molecular biology of the gene 4th edn, Benjamin-Cummings, 1987