Address: Department of Pharmacology, Monash University, Clayton, 3168
Studies on the properties of drugs which affect the cardiovascular system, particularly those which affect autonomic reflexes and vascular smooth muscle. The pharmacology of antihypertensive agents and eicosanoids. Vascular complications of diabetes. Studies of the effects of pregnancy on cardiovascular responses and the uterine vasculature. Pharmacological modulation of potassium ion channels. Pharmacological and biochemical investigations of the effects of drugs on smooth muscle within the reproductive tract. The effects of drugs on vascular function and transport in the human placenta. Drug receptors as membrane-bound enzyme systems. Hormonal modulation of drug receptors. Studies of the properties of newly synthesised novel compounds of potential therapeutic use (eg anti-HIV agents, neuroprotective drugs), in collaboration with chemists. Studies on the pharmacological properties of novel compounds extracted from marine organisms. Neurochemical studies of neurotransmission. Pharmacology of novel neuroprotective agents. Applications of fibre optic confocal imaging and microscopy in pharmacology. Applications of cell cultures for studying drug action.
Research in conjunction with Prince Henry's Institute of Medical Research
Monash Medical Centre, 246 Clayton Road, Clayton, 3168
The autonomic nervous system and cardiovascular control. Signal transduction processes in cardiac and vascular smooth muscle, receptors involved in modulation of transmitter release in the central nervous system. Hormonal regulation of the cardiovascular system.